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JUST OUT OF PRESS!

Check out our new article on autophagosome-lysosome mediated traffic of thrombopoietin receptor - READ MORE

PUBLISHED WORK

The Fruits of Our Labor

Uncovering Oncogenic Rouge Chaperones

Blood, 2019

Calreticulin mutants as oncogenic rogue chaperones for TpoR and traffic-defective pathogenic TpoR mutants 
C Pecquet*, I Chachoua*, A Roy*, T Balligand*, et al. 

Determinant of fate in cleavage furrows

Blood,2016

Activity of nonmuscle myosin II isoforms determines localization at the cleavage furrow of megakaryocytes 
A. Roy, L. Lordier, S. Mazzi, Y. Chang et al. 

Escape of Megakaryocytes

Haematologica, 2016

Uncoupling of the Hippo and Rho pathways allows megakaryocytes to escape the tetraploid checkpoint. 
A. Roy*, L. Lordier*, C. Pioche-Durieu, S. Souquere et al. 

MCM7 differential regulation

RNA Biology, 2014

Differential regulation of MCM7 and its intronic miRNA cluster miR-106b-25 during megakaryopoiesis induced polyploidy. 

Alteration in Mitochondrial proteome

Alteration of Mitochondrial Proteome Due to Activation of Notch1 Signaling Pathway.

SELECTED PUBLICATIONS

Differential mTORC2 regualtion by Type I and II CALR mutants of MPN

Cell Communication and Signaling, 2025

Differential regulation of mTORC2 signalling by type I and type II calreticulin (CALR) driver mutations of myeloproliferative neoplasm

Characterizing signalling cascade of zebrafish TpoR

Journal of Thrombosis and Haemostasis, 2025

Unconventional interaction of the zebrafish thrombopoietin receptor with Mapk14a determines thrombocyte development and function

Long-term thalidomide treatment and secondary B-ALL

Journal of Biological Chemistry, 2024

A pre-B acute lymphoblastic leukemia cell line model reveals the mechanism of thalidomide therapy-related B-cell leukemogenesis

A novel SNX2::ABL1 in Ph-like B-ALL

Pediatric Blood & Cancer, 2023

Detection of a novel SNX2 gene breakpoint in the SNX2::ABL1 fusion transcript in Ph‐like B‐cell acute lymphoblastic leukemia; Pediatric Blood & Cancer

Secreted mutant CALRs act as rogue cytokines in MPN

Blood, 2023

Secreted mutant calreticulins as rogue cytokines in myeloproliferatve neoplasms

A novel IKZF1::CIITA mutation in relapsed B-ALL

Pediatric Blood & Cancer, 2022

IKZF1::CIITA, a novel fusion transcript in a case of relapsed B-cell acute lymphoblastic leukemia

TpoR traffic - a review

J. Cellular & Molecular Medicine, 2021

In and out: Traffic and dynamics of thrombopoietin receptor

Oncogenic Rogue Chaperones in MPN

Blood, 2019

Calreticulin mutants as oncogenic rogue chaperones for TpoR and traffic-defective pathogenic TpoR mutants 
 

Motor Proteins and Polyploidy

Blood,2016

Activity of nonmuscle myosin II isoforms determines localization at the cleavage furrow of megakaryocytes 
 

Tetraploid Checkpoint in Megakaryocytes

Haematologica, 2016

Uncoupling of the Hippo and Rho pathways allows megakaryocytes to escape the tetraploid checkpoint. 
 

MCM7 and megakaryopoiesis

RNA Biology, 2014

Differential regulation of MCM7 and its intronic miRNA cluster miR-106b-25 during megakaryopoiesis induced polyploidy. 

Alteration in Mitochondrial proteome

Journal of Biological Chemistry, 2014

Alteration of Mitochondrial Proteome Due to Activation of Notch1 Signaling Pathway.

Notch1 intracellular domain function

Cell Death & Disease, 2012

NOTCH1 intracellular domain increases cytoplasmic EZH2 levels during early megakaryopoiesis. 

Click here to visit Google Scholar page for a complete list of publications

©2025 Anita Roy's Lab @ IIT Delhi.

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